NEW YORK, NY - AUGUST 31: Daria Gavrilova of Australia returns a shot against Shelby Rogers of the United States during their second round Women's Singles match on Day Four of the 2017 US Open at the USTA Billie Jean King National Tennis Center on August 31, 2017 in the Flushing neighborhood of the Queens borough of New York City. (Photo by Abbie Parr/Getty Images)

Australian Daria Gavrilova's US Open campaign is over, after losing in three sets to American Shelby Rogers in the longest ever women's match at the event.

Rogers defeated the 25th seed in a whopping three hours and 33 minutes, 7-6 (8-6), 4-6, 7-6 (7-5) to advance to the third round.

Gavrilova saved four match points and came back from a break down on three occasions to force the third set tiebreaker, showing her typical fighting spirit, before eventually succumbing to the home tow favourite.

The two players shared a long embrace following the epic encounter which featured a 90 minute decider.

Rogers will next face fourth seed, Ukrainian Elina Svitolina.

Gavrilova's exit leave Ash Barty as the sole Aussie left in the women's draw.