Querry, who had only beaten Murray once in eight attempts, reached his first Wimbledon semi-final with 3-6, 6-4, 6-7, 6-1, 6-1 win over the Brit.
The first set went to plan for the local crowd, with Murray claiming it with relative ease after securing an early break. Querry then rallied in the second, before Murray took out the third set tiebreak to take a two sets to one lead.
However, from there Murray was a shadow of himself, as he was visibly hampered by the hip injury he had carried into the tournament, which until this point, had appeared not to bother him at these Championships.
Querry lost just two games in the final two sets as he made the most of Murray’s injury, running him all over the court and pounding unreturnable serve after unreturnable serve.
The 29-year-old will face Marin Cilic in the semi-final, after he defeated Gilles Muller 3-6, 7-6, 5-7, 7-5, 6-1.
On the side of the draw, a red hot Roger Federer, who accounted for Milos Raonic in straight sets, will take on Tomas Berdych, who advanced after 2-time Grand Slam champion Novak Djokovic retired hurt, with the big Czech leading 7-6 and 2-0.
The men’s semi-finals will take place on Friday night AEST.